A microbiota and dietary metabolite integrates DNA repair and cell death to regulate embryo viability and aneuploidy during aging | Science Advances
Abstract During aging, environmental stressors and mutations along with reduced DNA repair cause germ cell aneuploidy and genome instability, which limits fertility and embryo development. Benevolent commensal microbiota and dietary plants secrete indoles, which improve healthspan and reproductive success, suggesting regulation of germ cell quality. We show that indoles
Published in: "Science Advances".