Oral polyphenol-armored nanomedicine for targeted modulation of gut microbiota–brain interactions in colitis | Science Advances

Abstract Developing oral nanomedicines that suppress intestinal inflammation while modulating gut microbiota and brain interactions is essential for effectively treating inflammatory bowel disease. Here, we report an oral polyphenol-armored nanomedicine based on tumor necrosis factor–α (TNF-α)–small interfering RNA and gallic acid–mediated graphene quantum dot (GAGQD)–encapsulated bovine serum albumin nanoparticle,

Published in: "Science Advances".